PD-L1 Biotin Labeled-ProtTech Inc.

  
     
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PD-L1 Biotin Labeled
PD-L1 is a ligand for program cell death 1 (PD1). PD-L1 suppresses immune response against tumor cells upon binding to PD1 receptor. PD-L1 is expressed on T and B cells, macrophages, dendritic cells, and some nonimmune cells. Antibody binding against PD-1 or PD-L1 leads to antitumor immunity. The C-terminal of this protein is biotinylated by biotin ligase.
  • Name: PD-L1 Biotin Labeled
  • Synonyms: Programmed cell death 1 ligand 1, PDCD1 ligand 1 Biotin Labeled
  • Catalogue Number:PT-OP-0003
  • Application:FOR LABORATORY RESEARCH USE ONLY.
  • Price: 50ug $200.00 100ug $350.00 1000ug $3000.00
  • Number:
  • Concentration:0.5mg/ml
  • Store:Avoid repeated freeze-thaw cycles. 12 months at -20 C to -80 C. 1 month at 2 C to 8 C.

Quality control assay: Correct disulfide bonds in PD-L1 were verified by Mass Spectrometry analyses. PD-L1 biotinylation is confirmed by streptavidin binding assay.


Accession #: Q9NZQ7


References:

  1. Hamanishi,  Junzo, et al. "Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human      ovarian cancer." Proceedings      of the National       Academy of Sciences 104.9 (2007): 3360-3365.

  2. Lin,      David Yin-wei, et al. "The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors." Proceedings of the National Academy of Sciences 105.8 (2008): 3011-3016.

 

Cat No.: PT-OP-0003
Product Name: PD-L1 Biotin Labeled
Type: Protein
Property:
Origin:
Source: E.coli
Application: FOR LABORATORY RESEARCH USE ONLY.
Formulation: 10 mM Bicine buffer at pH8.3, 50% glycerol.
Purity: >95% by SDS-PAGE gel
Storage: Avoid repeated freeze-thaw cycles. 12 months at -20 C to -80 C. 1 month at 2 C to 8 C.
Limitation:
Note: