Capping Enzymes-ProtTech Inc.

      
  
     
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Capping Enzymes
Eukaryotic RNA must undergo a series of modifications in order to be exported from the nucleus and successfully translated into function proteins, the first mRNA modification is capping.[1][2] 5' capping is essential for mRNA stability, enhancing mRNA processing, mRNA export and translation.[2]
  • Name: Capping Enzymes
  • Synonyms: D1, D12
  • Catalogue Number:PT-RNA-VCE-CAP
  • Application:Research in mRNA vaccine development
  • Price: 100ug $700 200ug $1400 1000ug $5000
  • Number:
  • Concentration:0.4mg/ml
  • Store:Avoid repeated freeze-thaw cycles. 12 months at -20 C to -80 C. 1 month at 2 C to 8 C.

Product Description: The capping enzyme is composed of two subunits: D1 and D12. Eukaryotic RNA must undergo a series of modifications in order to be exported from the nucleus and successfully translated into function proteins, the first mRNA modification is capping.[1][2] 5' capping is essential for mRNA stability, enhancing mRNA processing, mRNA export and translation.[2]


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Quality control: Verified by Mass Spectrometry analysis.


Product Source: Both D1 and D12 were produced in E. coli cells transformed with capping. This product is sterile and does not contain any components of animal origin.


Usage: FOR LABORATORY RESEARCH USE ONLY.


References:

  1. Watson J (April 8, 2014). Molecular Biology of the Gene. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. pp. 429–455. ISBN 9780321762436.

  2. Ghosh A, Lima CD (Jul–Aug 2010). "Enzymology of RNA cap synthesis". Wiley Interdisciplinary Reviews: RNA. 1 (1): 152–72. doi:10.1002/wrna.19. PMC 3962952. PMID 21956912.

Cat No.: PT-RNA-VCE-CAP
Product Name: Capping Enzymes
Type: Protein
Property:
Origin:
Source: E.coli
Application: Research in mRNA vaccine development
Formulation: Sterile filtered through a 0.2 micron filter in 50% glycerol, 10 mM MES buffer at pH 6.5
Purity: >95% by SDS-PAGE gel
Storage: Avoid repeated freeze-thaw cycles. 12 months at -20 C to -80 C. 1 month at 2 C to 8 C.
Limitation:
Note: