Recombinant Human TNF-alpha-ProtTech Inc.

  
     
Home > Product > Cell Factor
Recombinant Human TNF-alpha
Tumor necrosis factor (TNF-alpha) is a key regulator of the inflammatory response. TNF-alpha is involved in a diverse range of inflammatory conditions, including rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease and psoriasis. TNF-alpha binds to two different receptors, TNFR1 and TNFR2 to trigger immune responses. The physiological role of TNF-alpha has been highlighted by the use of anti-TNF antibody drug or soluble TNF receptor drug in inflammatory diseases.
  • Name: Recombinant Human TNF-alpha
  • Synonyms: Tumor necrosis factor, TNF, Cachectin, TNF-α
  • Catalogue Number:PT-CF-hTNFA-001
  • Application:FOR LABORATORY RESEARCH USE ONLY.
  • Price: 50ug $80.00 100ug $100.00 500ug $400.00
  • Number:
  • Concentration:0.5mg/ml
  • Store:Avoid repeated freeze-thaw cycles. 12 months at -20 C to -80 C. 1 month at 2 C to 8 C.


Sequence:
GPQREEFPRD LSLISPLAQA VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELRDNQLVV PSEGLYLIYS QVLFKGQGCP STHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAEINRPD YLDFAESGQV YFGIIAL

Acession #: P01375


Quality control: Verified by Mass Spectrometry analyses.


Product Source: TNF-alpha was produced in E. Coli cells transformed with human TNF-alpha gene. This product is sterile and does not contain any components of animal origin.


References:

  1. Bradley, J. R. (2008). TNF-mediated      inflammatory disease. The      Journal of pathology214(2),      149-160.

  2. Song, H. Y., Régnier, C. H., Kirschning, C. J.,      Goeddel, D. V., & Rothe, M. (1997). Tumor necrosis factor      (TNF)-mediated kinase cascades: bifurcation of nuclear factor-κB and c-jun      N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2. Proceedings of the National      Academy of Sciences94(18),      9792-9796.

Cat No.: PT-CF-hTNFA-001
Product Name: Recombinant Human TNF-alpha
Type: Protein
Property:
Origin:
Source: E.coli
Application: FOR LABORATORY RESEARCH USE ONLY.
Formulation: Sterile filtered through a 0.2 micron filter in 50% glycerol, 10 mM Tris buffer at pH 8, 50 mM NaCl
Purity: >95% by SDS-PAGE gel
Storage: Avoid repeated freeze-thaw cycles. 12 months at -20 C to -80 C. 1 month at 2 C to 8 C.
Limitation:
Note: