Recombinant Human Interleukin-4 (hIL-4)-ProtTech Inc.

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Recombinant Human Interleukin-4 (hIL-4)

Interleukin-4 (IL-4) is a lymphokine that has pleiotropic effects on both immune and non-immune cells. IL-4 stimulates the proliferation of activated B and T cells. IL-4 preferentially induced IgE and IgG4 production. IL-4 enhances the functional activities of myeloid cells, and the cytotoxic activity of lymphocytes and monocytes. IL-4 also shows inhibitory effect on the growth of chronic lymphocytic B-cells, and anti-tumor activity.

Name: Recombinant Human Interleukin-4 (hIL-4)
Synonyms: IL-4, BSF-1, Binetrakin, lymphocyte stimulatory factor 1, pitrakinra
Catalogue Number：PT-CF-hIL4-001
Application：Research
Price： 50ug $80 100ug $100 500ug $400
Number：
Concentration：1.0mg/ml
Store：Avoid repeated freeze-thaw cycles. 12 months at -20 C to -80 C. 1 month at 2 C to 8 C.

Sequence:.HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE NFLERLKTIM REKYSKCSS

Acession #: P05112

Quality control: Verified by Mass Spectrometry analyses and disulfide mapping.

Product Source: IL-4 was produced in E. Coli cells transformed with human IL-4 gene. This product is sterile and does not contain any components of animal origin.

Usage: FOR LABORATORY RESEARCH USE ONLY.

References:

Walter, M. R., Cook, W. J., Zhao, B. G., Cameron, R. P., Ealick, S. E., Walter, R. L., ... & Bugg, C. E. (1992). Crystal structure of recombinant human interleukin-4. Journal of Biological Chemistry, 267(28), 20371-20376.
Pene, J., Rousset, F., Brière, F., Chrétien, I., Bonnefoy, J. Y., Spits, H., ... & Banchereau, J. (1988). IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2. Proceedings of the National Academy of Sciences, 85(18), 6880-6884.

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Cat No.：	PT-CF-hIL4-001
Product Name：	Recombinant Human Interleukin-4 (hIL-4)
Type：	Protein
Property：
Origin：
Source：	E.coli
Application：	Research
Formulation：	Sterile filtered through a 0.2 micron filter in 50% glycerol, 10 mM Phosphate buffer at pH 7, 200 mM
Purity：	>95% by SDS-PAGE gel
Storage：	Avoid repeated freeze-thaw cycles. 12 months at -20 C to -80 C. 1 month at 2 C to 8 C.
Limitation：
Note：